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Karl Kunzelmann Selected Research

Anoctamins

1/2022Influence of Anoctamin-4 and -9 on ADAM10 and ADAM17 Sheddase Function.
3/2019Contribution of Anoctamins to Cell Survival and Cell Death.
1/2018Regulation of TMEM16A/ANO1 and TMEM16F/ANO6 ion currents and phospholipid scrambling by Ca2+ and plasma membrane lipid.
3/2016Modulating Ca²⁺ signals: a common theme for TMEM16, Ist2, and TMC.
2/2016Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage.
5/2014Anoctamin 1 induces calcium-activated chloride secretion and proliferation of renal cyst-forming epithelial cells.
3/2014Role of anoctamins in cancer and apoptosis.
3/2014Molecular functions of anoctamin 6 (TMEM16F): a chloride channel, cation channel, or phospholipid scramblase?
8/2011Anoctamins.

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Karl Kunzelmann Research Topics

Disease

39Cystic Fibrosis (Mucoviscidosis)
01/2022 - 01/2003
17Neoplasms (Cancer)
01/2022 - 06/2005
13Cysts
10/2021 - 10/2010
7Lung Diseases (Lung Disease)
11/2017 - 01/2003
5Asthma (Bronchial Asthma)
03/2022 - 01/2019
5Autosomal Dominant Polycystic Kidney (ADPKD)
10/2021 - 05/2014
5Scott Syndrome
12/2019 - 03/2014
5Diarrhea
06/2015 - 01/2002
4Infections
10/2021 - 11/2004
4Hemorrhage
03/2016 - 03/2014
4Carcinoma (Carcinomatosis)
07/2009 - 01/2007
3Chronic Obstructive Pulmonary Disease (COPD)
01/2022 - 01/2019
3Inflammation (Inflammations)
07/2021 - 11/2008
3Squamous Cell Carcinoma of Head and Neck
01/2020 - 01/2012
3Polycystic Kidney Diseases (Polycystic Kidney Disease)
01/2019 - 01/2016
3Inborn Genetic Diseases (Disease, Hereditary)
03/2015 - 01/2005
3Colonic Neoplasms (Colon Cancer)
08/2008 - 02/2007
2Thrombosis (Thrombus)
01/2019 - 11/2016
2Kidney Diseases (Kidney Disease)
01/2018 - 04/2014
2Hypoxia (Hypoxemia)
12/2016 - 03/2014
2Breast Neoplasms (Breast Cancer)
01/2012 - 02/2007
2Vitelliform Macular Dystrophy
02/2010 - 02/2008
2Acidosis
01/2010 - 06/2005
2Macular Degeneration (Age-Related Maculopathy)
02/2008 - 09/2007
1Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2022
1Respiratory Tract Infections (Respiratory Tract Infection)
01/2022
1Human Influenza (Influenza)
01/2022
1Pneumonia (Pneumonitis)
10/2021
1Metaplasia
05/2021
1COVID-19
05/2021
1Diseases Newborn Infant
01/2021
1Alkalosis
01/2020
1Head and Neck Neoplasms (Head and Neck Cancer)
01/2020
1Alzheimer Disease (Alzheimer's Disease)
12/2019
1Carcinogenesis
12/2019
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
03/2019
1Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
01/2019
1Communicable Diseases (Infectious Diseases)
01/2019
1Rupture
01/2018

Drug/Important Bio-Agent (IBA)

17Proteins (Proteins, Gene)FDA Link
01/2021 - 06/2002
16ChloridesIBA
03/2022 - 01/2007
16Chloride Channels (Chloride Channel)IBA
01/2022 - 04/2003
15Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA
04/2021 - 01/2004
9AnoctaminsIBA
01/2022 - 08/2011
9Pharmaceutical PreparationsIBA
01/2022 - 03/2015
9CalciumIBA
12/2019 - 11/2011
7ElectrolytesIBA
08/2012 - 01/2002
6NiclosamideFDA Link
01/2022 - 01/2019
6Anoctamin-1IBA
04/2021 - 05/2014
6Ion Channels (Ion Channel)IBA
01/2018 - 06/2005
5Phospholipids (Phosphatides)FDA LinkGeneric
03/2019 - 03/2014
5CollagenIBA
01/2019 - 03/2014
5Adenosine Triphosphate (ATP)IBA
01/2017 - 01/2010
5BestrophinsIBA
02/2010 - 09/2007
3Bicarbonates (Hydrogen Carbonate)IBA
01/2022 - 01/2017
3Small Interfering RNA (siRNA)IBA
01/2022 - 01/2012
3AnionsIBA
01/2020 - 10/2004
3Glucose (Dextrose)FDA LinkGeneric
01/2018 - 05/2011
2CytokinesIBA
01/2021 - 01/2019
2Biomarkers (Surrogate Marker)IBA
01/2020 - 01/2012
2Prolyl-Hydroxylase InhibitorsIBA
11/2018 - 03/2014
2Phosphotransferases (Kinase)IBA
01/2018 - 11/2011
2Adenosine Monophosphate (AMP)IBA
05/2014 - 11/2008
2ColforsinIBA
03/2014 - 11/2013
2SaltsIBA
09/2013 - 02/2007
2Phenylalanine (L-Phenylalanine)FDA Link
01/2013 - 04/2007
2IonsIBA
08/2012 - 11/2004
2Potassium Channels (Potassium Channel)IBA
01/2012 - 08/2008
2Large-Conductance Calcium-Activated Potassium Channels (Maxi-K Channels)IBA
01/2012 - 08/2008
2CationsIBA
10/2010 - 01/2006
2NucleotidesIBA
01/2009 - 04/2007
2Ether (Diethyl Ether)IBA
08/2008 - 02/2007
2Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA
02/2007 - 01/2007
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2022
1AntioxidantsIBA
10/2021
1Transcription Factors (Transcription Factor)IBA
07/2021
1polycystic kidney disease 2 proteinIBA
06/2021
1polycystic kidney disease 1 proteinIBA
06/2021
1Interleukin-8 (Interleukin 8)IBA
01/2021
1MucinsIBA
01/2021
1Interleukin-13IBA
01/2021
1SecretinFDA Link
01/2020
1BenzbromaroneIBA
01/2020
1RNA (Ribonucleic Acid)IBA
01/2020
1DisintegrinsIBA
12/2019
1Metalloproteases (Metalloproteinases)IBA
12/2019
1Phospholipases A2 (Phospholipase A2)IBA
03/2019
1Laminin (Merosin)IBA
01/2019
1nitazoxanide (NTZ)FDA Link
01/2019
1IntegrinsIBA
01/2019
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2019
1Glycoproteins (Glycoprotein)IBA
01/2019
1C-Type Lectins (C-Type Lectin)IBA
01/2019
1gluconic acid (gluconate)FDA LinkGeneric
01/2018
1LipidsIBA
01/2018
1InflammasomesIBA
01/2018
1Glutamine (L-Glutamine)FDA Link
01/2018

Therapy/Procedure

8Therapeutics
04/2021 - 01/2003
2Drug Therapy (Chemotherapy)
02/2007 - 01/2003
1Precision Medicine
11/2020